(R)-1-Boc-pyrrolidine-3-carboxylic acid methyl ester

(R)-1-Boc-pyrrolidine-3-carboxylic acid methyl ester - Names and Identifiers

Name	(R)-1-Boc-pyrrolidine-3-carboxylic acid methyl ester
Synonyms	(R)-Methyl 1-Boc-pyrrolid... (R)-1-Boc-pyrrolidine-1,3-dicarboxylate (R)-Methyl 1-Boc-pyrrolidine-3-carboxylate (R)-1-BOC-Pyrrolidine-3-carboxylic acid ethyl ester (R)-1-Boc-pyrrolidine-3-carboxylic acid methyl ester (R)-1-BOC-PYRROLIDINE-3-CARBOXYLIC ACID METHYL ESTER 1-tert-butyl 3-Methyl (3R)-pyrrolidine-1,3-dicarboxylate O1-tert-Butyl O3-methyl (3R)-pyrrolidine-1,3-dicarboxylate (3R)-1-tert-butoxycarbonyloxycarbonylpyrrolidine-3-carboxylic acid (R)-1-tert-Butoxycarbonyl-pyrrolidine-3-carboxylic acid methyl ester
CAS	441717-40-4
EINECS	1308068-626-2
InChI	InChI=1/C11H17NO6/c1-11(2,3)18-10(16)17-9(15)12-5-4-7(6-12)8(13)14/h7H,4-6H2,1-3H3,(H,13,14)/t7-/m1/s1

(R)-1-Boc-pyrrolidine-3-carboxylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C11H19NO4
Molar Mass	229.27
Density	1.301g/cm³
Boling Point	374.4°C at 760 mmHg
Flash Point	180.3°C
Vapor Presure	1.23E-06mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.507
Use	This product is for scientific research only and shall not be used for other purposes.

(R)-1-Boc-pyrrolidine-3-carboxylic acid methyl ester - Introduction

(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r)-(r-)-(r-)-(r-)-(r-)-(r-)-(acid-). Its chemical structure contains a protecting group (Boc group) and an ester group.

This compound is a colorless liquid at room temperature and has a low vapor pressure. Its molecular formula is C12H21NO4 and its molecular weight is 247.3g/mol. The melting point of this compound is about 44-46 degrees Celsius.

(R)-acid ester is often used in organic synthetic chemical reactions, especially in the synthesis of chiral drugs. It can be used as chiral inducer and synthesis intermediate of chiral compounds. In addition, it has applications in ligand synthesis, synthesis of chiral catalysts, and other chirally controlled reactions in organic synthesis.

The preparation of (R)-acid methyl ester usually uses pyrrolidine formic acid and methanol as raw materials. First, pyrrolidine carboxylic acid is reacted with an alcohol and an acid catalyst to form the corresponding ester. Then, the reaction solution can be neutralized with alkali to obtain (R)-acid methyl ester.

Regarding safety information, this compound generally has low toxicity, but care should be taken to avoid contact with skin, eyes and inhalation of its vapors. Good laboratory practices and personal protective measures, such as gloves, goggles and respiratory protective equipment, should be used. It should be stored in a dry, well-ventilated place to avoid contact with oxidants.

Last Update：2024-04-09 21:01:54